I think one of the gorgeous things about TG is that we will go from something amazingly serious and important and significant in terms of the world and life, and then do something ludicrous and absurd.
In any country when you’re going to make significant commitments, you have to look the head of state of that country eyeball to eyeball and say to them, ‘I’m going to make this commitment, and I’m counting on you and your commitments.’
There’s not much you can complain about – you’re a Major League Baseball player; you’re getting paid to play a game. People want to be you, wish they could do what you do. There are some complaints here and there, but there really aren’t any significant ones.
A good litmus test is that you should be comfortable with your significant other being present when you hang out with your friend.
My kids are young and my life with them is really stimulating and really full and significant.
Madam Speaker, before being elected to Congress, I ran a manufacturing business that did a significant percentage of our sales outside the United States.
I think isolationism is a mistake, no matter what party you see it in. We have to remember that there are two threats to our freedom: there’s a threat that comes from the federal government, from the Obama Administration policies… but there’s also a huge and significant threat from al-Qaeda.
It has always surprised me how little attention philosophers have paid to humor, since it is a more significant process of mind than reason. Reason can only sort out perceptions, but the humor process is involved in changing them.
The world is a mess, and while there is no simple pill America can administer to fix things, what we know is that there is significant room for progressives to articulate a foreign policy vision that is truly our own.
We can continue to make significant strides in the scientific community by exploring new stem cell research methods that do not include destroying human embryos.
With documentary-film projects, you hope you highlight an area of concern people haven’t thought about before. A lot of times, I’m asking myself – ‘This seems to be a significant problem. What can be done that hasn’t been done?’
At HSN, the experience we create are a significant point of differentiation.
The significant regulatory impact of reclassifying broadband services is not something that should be taken lightly and should not be done without additional direction from Congress.
Humor is by far the most significant activity of the human brain.
I guess the two Manifesto, Communicating Vessels, Mad Love, and some of his poetry made a significant mark on me but as far as bringing a literary element into the music I see it as a much broader assimilation.
Seventy-five percent of women who smoke would like to quit, and yet only two to three percent quit every year… It’s significant because we can help women quit smoking.
We’ve got to get rid of the stuff on the space station somehow. So we do have a pretty significant capability to bring back stuff on SpaceX that you might not imagine.
Significant cuts to funding for the police, for the Crown Prosecution Service, for probation etc, have put the long-term viability of our criminal justice system in doubt.
Economists are coming to acknowledge that measures of national wealth and poverty in terms strictly of average income tell you little that is significant of the health or viability of a society.
There’s no question that as science, knowledge and technology advance, that we will attempt to do more significant things. And there’s no question that we will always have to temper those things with ethics.
No one gives a damn what Iran thinks on any significant issue. The only reason Iran is at the big boys’ table is because of their nuclear weapons program.
Human bodies are designed for regular physical activity. The sedentary nature of much of modern life probably plays a significant role in the epidemic incidence of depression today. Many studies show that depressed patients who stick to a regimen of aerobic exercise improve as much as those treated with medication.
I felt invisible in my family, and I wanted to be significant like my brothers were significant. I wanted my parents to pay attention, so I went out into the world with that driving me, that grasping, that seeking validation.
Your memorabilia becomes more significant. It does put you in a different category.
I did drama school in Delhi. I am glad I studied in a school where cultural activities were significant.
What the Olympics and other mega-events have shown is that the significant investment required to host an international games successfully has the power to transform a region, and even a nation.
Most presidents have not considered 100 days a significant milepost.
There are a significant number of people who appreciate what we do, and most of them gravitate to Analog because this is where they can find it. The other magazines tend to share their audiences, which may result in each of them having a smaller market share.
Women artists, no matter how well recognized they are, are seldom given solo exhibitions or featured in significant group shows. They are never top-ranked in auction choices.
You look at guys with significant Alzheimer’s and dementia and the mood swings and the suicides that unfortunately NFL players have been faced with. And depression. Lou Gehrig’s disease. These are all things that have kind of been linked to the brain damage from football.
In Italy, there are so many significant architectural structures in history such as the Pantheon in Rome, or the Duomo.
Washington, D.C., is the new Wall Street. No significant financial transaction of any consequence occurs without it.
I felt that Stephen had become such a significant figure, a scientist of such international renown, that at some future date, someone would be sure to attempt an inaccurate, sensationalised biography, possibly including me, possibly writing me out of the script.
The Tea Party definitely scored a significant victory with Senator Cruz’s election in 2012 and scored victories in some statewide primaries. But to me, as the Tea Party gets stronger within the Republican Party in Texas, the prospect of a blue Texas becomes stronger and stronger.
The word ‘populism’ was everywhere in 2016. Political leaders claiming to speak for the people have achieved significant victories in Europe, Asia, and, with the election of Donald Trump, the United States.
I think the most significant change in my life is the decision to do a series. An hourlong dramatic television series on a broadcast network swallows you and chews you up and refuses to spit you out. You’re making a decision that’s going to be a profound and significant impact on the practical aspects of your life.
Crossroads fights are an important part of boxing. The winner goes on to bigger and better things, while the loser squanders a significant career opportunity.
Despite amazing advances in fertility to help older women get pregnant, the complications, increased chances of autism, and chromosomal abnormalities are significant considerations.
The birth of the baby Jesus stands as the most significant event in all history, because it has meant the pouring into a sick world the healing medicine of love which has transformed all manner of hearts for almost two thousand years.
A significant U.S. troop presence in Afghanistan has been continuous since October 2001, and President Obama’s short-lived ‘surge’ in 2009 was a continuation of his predecessor’s buildup there.
The anti-Darwin movement has racked up one astounding achievement. It has made a significant proportion of American parents care about what their children are taught in school.
We are seeing significant growth in foreign investment in Germany.
I’m not naive enough to pretend that on its own cinema can capture the very soul of significant social and cultural problems.
What makes things memorable is that they are meaningful, significant, colorful.
It is a significant acknowledgment that the way people are watching television is changing and the model is quickly changing.
What’s great about having a sci-fi/fantasy show start on the web: that’s a gigantic part of your demographic right there. It targets a significant part of your demographic when you deliver online.
A significant fraction of evangelical voters appear more likely to ignore the candidates’ specific economic and foreign policy platforms in favor of concerns about gay marriage or abortion.
If you look at all the companies I’ve been involved with – Flickr, Etsy, Findery – communities are a significant part of them. Connecting people to each other, user-generated content, building interactions. That’s what I’ve cared about most.
I stole a significant amount of money from a family member. I knew I was going to get caught, but I was so desperate I didn’t care. It was a cry for help.
Chaga is significant in ethnomycology, forest ecology, and increasingly in pharmacognosy. Its long-term human use and cultural eastern European and Russian acceptance should awaken serious researchers to its potential as a reservoir of new medicines, and as a powerful preventive ally for protecting DNA.
Particularly over the last few decades, technological innovation has offered opportunities to bring people and nations together – but it has also created significant new challenges to law enforcement.
